Mercier, F. published the artcileThe antispasmodic action of several benzyl derivatives of α-aminopyridine, Application of N-(4-Methoxybenzyl)pyridin-2-amine, the publication is Travaux de la Societe de Pharmacie de Montpellier (1947), 131-4, database is CAplus.
2-(4-Methoxybenzylamino)pyridine (I) (m.p. 120-1°), 2-(3,4-dimethoxybenzylamino)pyridine (II) (m.p. 165°), and 2-(3,4-methylenedioxybenzylamino)pyridine (III) (m.p. 96°) were prepared from the appropriate aldehyde and 2-aminopyridine in the presence of Na (cf. Funke and Fourneau, C.A. 38, 3262.8). At concentrations of 1:12,500 and 1:25,000 in Tyrode solution all 3 compounds depressed the tonus and activity of isolated rabbit intestine preparations Their action in this regard was inferior to that of papaverine. The spasms produced in the isolated intestine by acetylcholine or BaCl2 were diminished by all 3 compounds (spasmolytic action). The order of effectiveness was: I > III > II. By administration prior to the BaCl2 the spasm could be suppressed by I, somewhat diminished by III, but unmodified by II. None of the compounds had any effect on the spasm when administered prior to acetylcholine.
Travaux de la Societe de Pharmacie de Montpellier published new progress about 52818-63-0. 52818-63-0 belongs to ethers-buliding-blocks, auxiliary class Pyridine,Amine,Benzene,Ether, name is N-(4-Methoxybenzyl)pyridin-2-amine, and the molecular formula is C13H14N2O, Application of N-(4-Methoxybenzyl)pyridin-2-amine.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem