Jin, Kang published the artcileSynthesis and structure-activity relationship of teixobactin analogues via convergent Ser ligation, Formula: C25H23NO4, the publication is Bioorganic & Medicinal Chemistry (2017), 25(18), 4990-4995, database is CAplus and MEDLINE.
Convergent Ser/Thr ligation has been used to prepare a series of teixobactin analogs (28 in total) to establish a structure-activity relationship of teixobactin. anti-bacterial evaluations of these synthetic analogs have revealed the critical amino acid residues and the sites tolerable of modifications. These studies will shed lights on the further development of teixobactin analogs with improved antibacterial activities.
Bioorganic & Medicinal Chemistry published new progress about 77128-73-5. 77128-73-5 belongs to ethers-buliding-blocks, auxiliary class Inhibitor, name is (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-phenylpropanoic acid, and the molecular formula is C25H23NO4, Formula: C25H23NO4.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem