Blank, Benoit published the artcileSelective iridium-catalyzed alkylation of (hetero)aromatic amines and diamines with alcohols under mild reaction conditions, Application of N-(4-Methoxybenzyl)pyridin-2-amine, the publication is Chemistry – A European Journal (2009), 15(15), 3790-3799, database is CAplus and MEDLINE.
A P,N-ligand-coordinated iridium complex has been employed as an efficient catalyst for the selective monoalkylation of (hetero)aromatic amines with alcs. A significant improvement of this alkylation method has been achieved, such that it can be performed at a temperature of 70°C and with catalyst loadings as low as 0.1 mol% Ir, while still affording excellent yields of secondary amines. Furthermore, the high selectivity of this catalyst for the monoalkylation of aromatic amino functions has been successfully exploited for the alkylation of diamines in both sym. and nonsym. fashions, providing a novel and very efficient synthetic tool for the preparation of N,N’-dialkylated aromatic diamines.
Chemistry – A European Journal published new progress about 52818-63-0. 52818-63-0 belongs to ethers-buliding-blocks, auxiliary class Pyridine,Amine,Benzene,Ether, name is N-(4-Methoxybenzyl)pyridin-2-amine, and the molecular formula is C13H14N2O, Application of N-(4-Methoxybenzyl)pyridin-2-amine.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem