Grover, Madhuri published the artcilePhytochemical Screening, antioxidant Assay and Cytotoxic Profile for Different Extracts of Chrysopogon zizanioides Roots, Formula: C11H16O2, the main research area is Chrysopogon root extract antioxidant cytotoxic; antioxidant; cancer; chemotherapy; cytotoxicity; vetiver.
The Chrysopogon zizanioides plant possesses multiple traditional uses, especially in therapeutics, but only a few articles have reported its biol. activity. Hence, the present study was planned to explore the phytochem. constituents, cytotoxic potential, radical scavenging activity, and GC/MS (Gas chromatog. & Mass spectrometry) anal. of the vetiver root extracts The roots extracted with different solvents exhibited more significant phytochem. constituents in polar solvents in comparison to non-polar ones, favoring the extraction of a greater number of components in highly polar solvents. All the extracts were tested for their cytotoxicity using SRB (Sulforhodamine B) assay. They confirmed ethanolic extract as a potent extract with GI50 56±0.5 μg/mL in oral cancer (SCC-29B) along with no cytotoxicity in healthy cells (Vero cells), making it a safer therapeutic option in comparison to standard Adriamycin. This extract was also analyzed for its antioxidant potential by DPPH (1,1-Diphenyl-2-picrylhydrazyl) assay with IC50 value 10.73 μg/mL, which was quite comparable to Ascorbic acid having IC50 value 4.61 μg/mL. The quant. anal. of ethanolic extract exhibited 107 compounds amongst which Khusenic acid, Ascorbic acid, Junipen, gamma-Himachalene, alpha-Guaiene were the majorly occurring compounds that can be explored further for their cytotoxic activity.
Chemistry & Biodiversity published new progress about Antioxidants. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Formula: C11H16O2.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem