Zeng, Bo published the artcileOn the origin of nitrogen-containing promoters in the cobalt-catalyzed methoxycarbonylation of epoxides, COA of Formula: C4H10O2, the publication is Applied Catalysis, A: General (2021), 118291, database is CAplus.
The detailed promotion mechanism of nitrogenous compounds in the cobalt-catalyzed methoxycarbonylation of epoxides has not been studied to date. Herein, we present the intrinsic correlation between nitrogenous promoters and activity and selectivity in the alkoxycarbonylation of epoxides by a comprehensive in situ IR spectroscopy and DFT studies. In situ IR spectroscopy confirmed the acid-base neutralization of the nitrogenous promoters and HCo(CO)4, resulting in reduction of the acidity of the catalyst. With the reduced acid-derived activity for formation of ethers as byproducts, the selectivity of desired esters was increased. DFT calculations showed that a nitrogenous base could facilitate the methanolysis of cobalt-acyl species with lowered activation energy, which is considered to be the rate-determining step in the catalytic cycle. As a result, the reaction activity towards carbonylation was also improved by nitrogenous promoters. The present studies will provide new insights to the long-term confusing problems in epoxides carbonylation.
Applied Catalysis, A: General published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C5H6BNO2, COA of Formula: C4H10O2.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem