Liu, Zhizhou published the artcileThe danger of dichloromethane in the synthesis and application of imidazole-based dyes, Application In Synthesis of 134-96-3, the publication is Dyes and Pigments (2022), 110404, database is CAplus.
In this paper, a lophine-based phenol compound (I) has been prepared and identified as an efficient chromophore for the determination of hydrogen peroxide (H2O2) with enzymic method. A dry chem. analytic agent was also prepared involving this compound, showing good accuracy in the determination of uric acid. However, a commonly used solvent dichloromethane (DCM) could react with this imidazole derivative when the reaction mixture was irradiated under UV (365 nm). We explored the possible mechanism and identified several byproducts caused by the acidity and UV oxidation of DCM. Caution should be taken in the synthesis and application of such imidazole-based dyes in DCM, especially when phenol group was introduced to the imidazole moiety.
Dyes and Pigments published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Application In Synthesis of 134-96-3.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem