Hamby, Taylor B. published the artcileControlling Ni redox states by dynamic ligand exchange for electroreductive C(sp3)-C(sp2) coupling, Category: ethers-buliding-blocks, the publication is Science (Washington, DC, United States) (2022), 376(6591), 410-416, database is CAplus and MEDLINE.
Cross-electrophile coupling (XEC) reactions of aryl and alkyl electrophiles are appealing but limited to specific substrate classes. Here, electroreductive XEC of previously incompatible electrophiles including tertiary alkyl bromides, aryl chlorides, and aryl/vinyl triflates are reported. The reactions rely on the merger of an electrochem. active complex that selectively reacts with alkyl bromides through 1e– processes and an electrochem. inactive Ni0(phosphine) complex that selectively reacts with aryl electrophiles through 2e– processes. Accessing Ni0(phosphine) intermediates is critical to the strategy but is often challenging. Here, a previously unknown pathway for electrochem. generating these key complexes at mild potentials through a choreographed series of ligand-exchange reactions has been uncovered. The mild methodol. is applied to the alkylation of a range of substrates including natural products and pharmaceuticals.
Science (Washington, DC, United States) published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Category: ethers-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem