Dalla Cort, Antonella published the artcileInherently Chiral Uranyl-Salophen Macrocycles: Computer-Aided Design and Resolution, COA of Formula: C10H14O, the publication is Journal of Organic Chemistry (2005), 70(24), 9814-9821, database is CAplus and MEDLINE.
A flipping motion rapidly inverts the bent structure of uranyl-salophen compounds and, consequently, causes fast enantiomerization of nonsym. substituted derivatives This process was previously slowed by introducing bulky substituents in the imine bond region. Since the resulting complexes dissociate upon chromatog. treatment, an alternative approach to the design and synthesis of robust, nonflipping uranyl-salophen compounds is here described. Such an approach is based on the idea that the flipping motion would be blocked by connecting the para positions with respect to the phenoxide oxygens by polymethylene bridges of suitable length. Anal. of a number of uranyl-salophen compounds by mol. mechanics, while showing that bulky substituents in the imine bond region cause severe distortions of the ligand backbone, suggested that the best chain lengths are those that fit the gap between the phenoxide rings without altering the natural geometry of the parent uranyl-salophen compound Calculations showed that such chains are those composed of 12 and 13 methylene units. Accordingly, chiral uranyl-salophen macrocycles bridged with 12- and 13-methylene chains, [UO2(L)] (H2L = I, n = 1, 2; R = i-Pr, R’ = Ph), were synthesized in fairly good yields and resolved by chiral HPLC.
Journal of Organic Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, COA of Formula: C10H14O.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem