Thoma, K. published the artcileColloid association and biological availability of local anesthetics. Part 1. Surface activity studies on critical micelle concentrations, Formula: C17H28ClNO3, the publication is Pharmaceutica Acta Helvetiae (1988), 63(2), 34-9, database is CAplus and MEDLINE.
Surface activities of local anesthetics are reported. The ability to associate to micelles in aqueous solution was found with 9 benzoic acid esters, 3 anilides or acid amides, and for all compounds with ether structures. Twelve of the 29 investigated compounds do not associate to micelles. The critical micelle concentrations (CMC) in 0.9% NaCl solution range from 6.0·10-5 mol/L for the nonionic polydocanol to 6.6·10-2 mol/L for cornecaine-HCl. Cyclomethycaine has the lowest CMC (4.3·10-4 mol/L) of basic local anesthetics.
Pharmaceutica Acta Helvetiae published new progress about 637-58-1. 637-58-1 belongs to ethers-buliding-blocks, auxiliary class Inhibitor, name is 4-(3-(4-Butoxyphenoxy)propyl)morpholine hydrochloride, and the molecular formula is C9H12BClO3, Formula: C17H28ClNO3.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem