Pompeo, Matthew’s team published research in Angewandte Chemie, International Edition in 51 | CAS: 2944-47-0

Angewandte Chemie, International Edition published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Safety of 2-Isopropylanisole.

Pompeo, Matthew published the artcilePd-PEPPSI-IPentCl: A Highly Effective Catalyst for the Selective Cross-Coupling of Secondary Organozinc Reagents, Safety of 2-Isopropylanisole, the publication is Angewandte Chemie, International Edition (2012), 51(45), 11354-11357, database is CAplus and MEDLINE.

A series of Pd-PEPPSI complexes with various substitution pattern on the heterocyclic carbene backbone were designed, prepared and studied as catalysts in Negishi cross-coupling reactions of aryl and heteroaryl halides or triflates with secondary organozinc nucleophiles. In all the cases, the selectivity for the normal, non-rearranged products was observed Computational studies revealed that the relative barrier difference between reductive elimination and β-hydride elimination correlate well with observed selectivities. The best results were shown by the Pd-PEPPSI-IPentcl complex which demonstrated unprecedented selectivity leading to virtually one (desired) isomer for reactions of a wide selection of alkylzincs and highly functionalized (hetero)aromatic halides and triflates.

Angewandte Chemie, International Edition published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Safety of 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem