Li, Chengxi published the artcileEfficient Synthesis of Sterically Hindered Arenes Bearing Acyclic Secondary Alkyl Groups by Suzuki-Miyaura Cross-Couplings, Application In Synthesis of 2944-47-0, the publication is Angewandte Chemie, International Edition (2015), 54(12), 3792-3796, database is CAplus and MEDLINE.
Bulky P,P:O ligands I (R = H, OMe, NMe2) were designed and synthesized to inhibit isomerization and reduction side reactions during the cross coupling between sterically hindered aryl halides and alkylboronic acids. Suzuki-Miyaura cross-couplings between di-ortho-substituted aryl bromides and acyclic secondary alkylboronic acids using one of these ligands were achieved with high yields. The method also enabled the preparation of ortho-alkoxy/di-ortho-substituted arenes bearing iso-Pr groups in excellent yields. The utility of the synthetic method was demonstrated in a late-stage modification of estrone and in the application to a new synthetic route towards gossypol.
Angewandte Chemie, International Edition published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Application In Synthesis of 2944-47-0.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem