Kitson, Trevor M.’s team published research in Biochemical Pharmacology in 28 | CAS: 14807-75-1

Biochemical Pharmacology published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, HPLC of Formula: 14807-75-1.

Kitson, Trevor M. published the artcileStudies on possible mechanisms for the interaction between cyanamide and aldehyde dehydrogenase, HPLC of Formula: 14807-75-1, the publication is Biochemical Pharmacology (1979), 28(17), 2551-6, database is CAplus and MEDLINE.

Cyanamide (I) [420-04-2] reacted with amino and thiol groups to form guanidino and isothiouronium compounds resp. under physiol. conditions. Sheep liver cytoplasmic aldehyde dehydrogenase (II) [9028-86-8] activity in vitro was not affected by I (1-50 mM), dicyandiamide [461-58-5] (1 mM), or the aminoethylisothiouronium bromide-HBr (III) [56-10-0] (1 mM). Formamidine disulfide-2HCl [14807-75-1] (10-20 μM) inhibited II activity in vitro, but thiourea [62-56-6] (50 mg/kg, i.p. daily for 5 days) and III, (200 mg/kg, i.p., daily for 5 days) did not affect II activity in rat liver in vivo in either cytoplasm or mitochondria. The possible modes of action of I on alc. metabolism are discussed.

Biochemical Pharmacology published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, HPLC of Formula: 14807-75-1.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem