Diem Ferreira Xavier, Mauricio Carpe’s team published research in Tetrahedron in 120 | CAS: 6850-57-3

Tetrahedron published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Recommanded Product: (2-Methoxyphenyl)methanamine.

Diem Ferreira Xavier, Mauricio Carpe published the artcileDitelluride-Catalyzed synthesis of phosphoramidates: A design of experiment approach, Recommanded Product: (2-Methoxyphenyl)methanamine, the publication is Tetrahedron (2022), 132879, database is CAplus.

Di-Ph ditelluride Ph2Te2 in aerial oxidative conditions catalyzes amidation of hydrophosphonates HP(O)(OR2)2 (R2 = Et, Me, Bu) with primary and secondary amines RR1NH (R1 = H, R = alkyl, aralkyl; R = R1 = Et, RR1NH = pyrrolidine, morpholine), giving phosphoramidates RR1NP(O)(OR2)2 with high yields in mild conditions (50°, 13 mol% of Ph2Te2). In this contribution, we describe a selective synthesis of phosphoramidates employing di-Ph ditelluride as a simple and readily available organic catalyst. To optimize the reaction conditions, a full factorial design was carried out, demonstrating that the temperature is the critical factor for the P(O)-N bonding formation. The products were obtained in moderate to excellent yields, in mild conditions. Addnl., 31P and 125Te NMR spectroscopies were used to characterize the intermediate, confirming the reaction mechanism.

Tetrahedron published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Recommanded Product: (2-Methoxyphenyl)methanamine.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem