Ramachandran, P. Veeraraghavan published the artcileStudies towards the synthesis of epothilone A via organoboranes, Formula: C21H37BO, the publication is Organic & Biomolecular Chemistry (2005), 3(20), 3812-3824, database is CAplus and MEDLINE.
Studies towards the synthesis of epothilone A via organoboranes have been described. A modified procedure for the large-scale preparation of B-γ,γ-dimethylallyldiisopinocampheylborane from prenyl alc. has been developed. This reagent, upon reaction with various aldehydes RCHO (R = Et, Ph, 4-MeOC6H4CH2OCH2CH2, etc.), provides the corresponding α,α-dimethylhomoallylic alcs. I in high enantioselectivities. The application of this reagent for the synthesis of the C1-C6 subunit II of epothilone has been demonstrated. Alternatively, inter- and intramol. asym. reduction protocols have also been utilized for the synthesis of the C1-C6 subunit of epothilone A. The synthesis of the C7-C21 fragment III of epothilone A involving asym. alkoxyallyl- and crotylboration using α-pinene-derived reagents has also been described.
Organic & Biomolecular Chemistry published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Formula: C21H37BO.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem