Wang, Zijing published the artcileSonogashira reactions of alkyl halides catalyzed by NHC [CNN] pincer nickel(II) complexes, Safety of (2-Chloroethoxy)benzene, the main research area is nickel CNN pincer NHC carbene complex preparation Sonogashira catalyst; Sonogashira coupling catalyst nickel carbene pincer complex preparation; crystal structure nickel CNN pincer imidazolylidene carbene complex; mol structure nickel CNN pincer imidazolylidene carbene complex.
CNN-Pincer carbene nickel complexes I (6-8; R = iPr, Bu, PhCH2; X = Cl Br) were prepared and evaluated as catalysts for Sonogashira coupling of alkyl halides. The catalytic performance of complexes 6-8 for Sonogashira cross-coupling reactions was explored. In a combination of 5 mol% catalyst loading of 6 and CuI/Cs2CO3/NaI/DMSO at different temperatures for the coupling reactions between alkyl iodides, bromides, chlorides and terminal alkynes, the corresponding coupling products were obtained in moderate to excellent yields. The mechanism of these catalytic reactions was discussed and partially supported by experiments The phenylethynyl CNN pincer nickel complex 9 as a catalytically active complex was isolated and structurally characterized using X-ray diffraction.
New Journal of Chemistry published new progress about Alkynes, internal Role: SPN (Synthetic Preparation), PREP (Preparation). 622-86-6 belongs to class ethers-buliding-blocks, name is (2-Chloroethoxy)benzene, and the molecular formula is C8H9ClO, Safety of (2-Chloroethoxy)benzene.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem