Mizuno, Kazuhiko’s team published research in Synthesis in 1979-09-30 | CAS: 622-86-6

Synthesis published new progress about Dehydrohalogenation. 622-86-6 belongs to class ethers-buliding-blocks, name is (2-Chloroethoxy)benzene, and the molecular formula is C8H9ClO, Synthetic Route of 622-86-6.

Mizuno, Kazuhiko published the artcileA convenient synthesis of aryl vinyl ethers by use of tetrabutylammonium hydrogen sulfate, Synthetic Route of 622-86-6, the main research area is aryl vinyl ether; dehydrohalogenation haloethoxybenzene.

RC6H4OCH:CH2 (I; R = H, Me, Me3C, MeO, CN, halo, benzo) were prepared by dehydrohalogenation of RC6H4OCH2CH2X (II) in the presence of Bu4N+ HSO4- (III). Thus, 50% aqueous NaOH and 5 mmol III were added to a solution of 5 mmol II (R = 4-Me3C, X = Cl) in C6H6 and the mixture stirred 1 h at room temperature to give 97% I (R = 4-Me3C). Similarly prepared were 10 addnl. I.

Synthesis published new progress about Dehydrohalogenation. 622-86-6 belongs to class ethers-buliding-blocks, name is (2-Chloroethoxy)benzene, and the molecular formula is C8H9ClO, Synthetic Route of 622-86-6.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem