Khalaf, Juhienah published the artcileDesign, Synthesis, and Diversification of 3,5-Substituted Enone Library, Quality Control of 127972-00-3, the main research area is enone combinatorial library preparation; bromoenone preparation boronic acid Suzuki coupling; terminal alkyne bromoenone Sonogashira coupling; triazole preparation.
This paper describes the synthesis of a 300 member library of 3,5-substituted enones, e.g., I. The synthesis starts with six different bromoenones that are accessed from the corresponding 1,3 diones. These bromides are then diversified by Suzuki coupling with a variety of aromatic and vinyl boronic acids. Addnl. a small series of triazoles, e.g., II, were synthesized by a Sonogashira coupling reaction dipolar cycloaddition sequence. The library was analyzed by principal component anal. to examine its diversity.
ACS Combinatorial Science published new progress about Alkynes, α- Role: RCT (Reactant), RACT (Reactant or Reagent). 127972-00-3 belongs to class ethers-buliding-blocks, name is 2-Methoxy-5-methylphenylboronic acid, and the molecular formula is C8H11BO3, Quality Control of 127972-00-3.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem