Hielscher, Maximilian published the artcileOptimization Strategies for the Anodic Phenol-Arene Cross-Coupling Reaction, Product Details of C11H16O2, the main research area is phenol bezene regioselective electrochem dehydrogenative cross coupling; hydoxyphenyl benzene preparation.
Dehydrogenative phenol-arene cross-coupling by direct anodic oxidation is a promising alternative to reductive cross-coupling, especially for construction of smaller mols. The reaction pathway via phenoxyl radicals allows for unusual regioselectivity. Nevertheless, the numerous electrolysis parameters pose a challenge for optimization, as they determine the yield and selectivity of the reaction. Using design of experiments, optimization strategies for two example reactions to improve the space-time yield were reported. In particular, coupling reactions with 2,6-dimethoxyphenol (syringol) were found to be very robust in the electrolysis at high current densities of up to 150 mA/cm2. Cyclic voltammetry was used to classify combinations of phenols and arenes, on the basis of which the various clusters were optimized. Based on this classification, various biaryls were synthesized and isolated in yields of up to 85%.
ChemElectroChem published new progress about Benzenoid aromatic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Product Details of C11H16O2.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem