Hardcastle, Ian R. published the artcile4′-Substituted analogs of idoxifene: antiestrogens and calmodulin antagonists, Recommanded Product: (2-Chloroethoxy)benzene, the main research area is idoxifene analog preparation antiestrogen; calmodulin antagonist idoxifene analog.
4′-Substituted analogs, e.g. I, of the antiestrogen idoxifene have been prepared All the compounds were assayed for antagonism of calmodulin dependent c-AMP phosphodiesterase and for binding to rat uterine estrogen receptor. The 4′-amino compound I was the most potent antiestrogen (RBA = 47) while retaining a similar calmodulin antagonism to idoxifene.
Bioorganic & Medicinal Chemistry Letters published new progress about Calmodulins Role: BAC (Biological Activity or Effector, Except Adverse), BSU (Biological Study, Unclassified), BIOL (Biological Study). 622-86-6 belongs to class ethers-buliding-blocks, name is (2-Chloroethoxy)benzene, and the molecular formula is C8H9ClO, Recommanded Product: (2-Chloroethoxy)benzene.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem