Gao, Peng-Cheng published the artcileOxidative phenol-arene and phenol-phenol cross-coupling using periodic acid, Application of 4-Hydroxy-3-tert-butylanisole, the main research area is biaryl preparation; arene phenol oxidative cross coupling reaction; phenol oxidative cross coupling reaction; naphthol phenol oxidative cross coupling reaction.
A simple, metal-free protocol for unsym. biaryl coupling using H5IO6 is reported. H5IO6 was evaluated for a novel application in the oxidative cross-coupling of phenol-arene, phenol-phenol, and phenol-naphthol compounds ROH (R = 2,6-dimethoxyphenyl, 2-naphthyl, 5,6,7,8-tetrahydronaphthalen-2-yl, etc.) and R1H (R1 = 2,4,5-trimethoxyphenyl, 2-methoxynaphth-1-yl, N,N-dibenzyl-4-aminophenyl, etc.). In this work, most of the couplings were completed within 30 min at ambient temperature 30 coupling products, e.g., 4-(2-(dimethylamino)naphthalen-1-yl)-2,6-dimethylphenol were conveniently obtained using only 0.5 equiv of H5IO6 in HFIP. A mechanism by which the transformation occurs is proposed.
Tetrahedron published new progress about Aromatic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Application of 4-Hydroxy-3-tert-butylanisole.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem