Efficient Stereoselective Carbocyclization to cis-1,4-Disubstituted Heterocycles Enabled by Dual Pd/Electron Transfer Mediator (ETM) Catalysis was written by Zhu, Can;Liu, Jie;Mai, Binh Khanh;Himo, Fahmi;Baeckvall, Jan-E.. And the article was included in Journal of the American Chemical Society in 2020.SDS of cas: 1003858-50-1 The following contents are mentioned in the article:
In the presence of Pd(OAc)2 and a bis(hydroxyphenyl)salen cobalt complex acting as an electron transfer mediator, allylic enallenyl ethers such as I underwent diastereoselective tandem aerobic coupling and cyclization reactions with arylboronic acid neopentyl glycol esters to yield (arylmethyl)dialkenyldihydropyrans such as II and a dialkenyltetrahydropyridine as the cis-diastereomers in >8:1 dr. The mechanism of the reaction was studied using kinetic isotope effect (KIE) experiments, reactions of substrates with altered structures, and calculations of potential transition state structures and their energies; the alkene moiety of the eneallene is necessary both to facilitate C-H bond cleavage and to control product diastereoselectivity, while KIE indicated that C-H bond cleavage is the rate-limiting step. This study involved multiple reactions and reactants, such as 2-(3-Methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 1003858-50-1SDS of cas: 1003858-50-1).
2-(3-Methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 1003858-50-1) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.SDS of cas: 1003858-50-1
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem