Beyond Directed Ortho Metalation: Ruthenium-Catalyzed Amide-Directed CAr-N Activation/C-C Coupling Reaction of Anthranilamides with Organoboronates was written by Zhao, Yigang;Snieckus, Victor. And the article was included in Organic Letters in 2014.Electric Literature of C12H17BO3 The following contents are mentioned in the article:
A new, catalytic, and general methodol. for the synthesis of biaryls and heterobiaryls by the cross coupling of anthranilamide derivatives (o-NMe2 benzamides) with aryl boroneopentylates is described. The reaction proceeds under catalytic RuH2(CO)(PPh3)3 conditions driven by the activation of the unreactive C-N bond by amide directing group (DG)-Ru catalyst chelation. E.g., in presence of RuH2(CO)(PPh3)3 in toluene, reaction of aryl boroneopentylate (I) with 2-Me2NC6H4CONEt2 gave 99% biaryl derivative (II). High regioselectivity, orthogonality with the Suzuki-Miyaura reaction, operational simplicity, and convenient scale-up are features of these reactions which may lend themselves to industrial applications. This study involved multiple reactions and reactants, such as 2-(3-Methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 1003858-50-1Electric Literature of C12H17BO3).
2-(3-Methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 1003858-50-1) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Electric Literature of C12H17BO3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem