Intramolecular Oxidative Coupling between Unactivated Aliphatic C-H and Aryl C-H Bonds was written by Liao, Yang;Zhou, Yi;Zhang, Zhen;Fan, Junzhen;Liu, Feng;Shi, Zhangjie. And the article was included in Organic Letters in 2021.Name: 4-Benzyloxyphenol The following contents are mentioned in the article:
In this article, a Pd-catalyzed intramol. oxidative coupling between unactivated aliphatic and aryl C-H compounds ROCH2C(CH3)2CO2H (R = C6H5, 4-ClC6H4, 2-naphthyl, etc.) has been described. This chem. showed great potential to build up fused cyclic scaffolds I (R1 = H, Me, OMe; R2 = Me, Ph, F, etc.; R3 = H, Me; R4 = H, Me; R1R2 = R3R4 = -CH=CHCH=CH-) and 3-methyl-3,4-dihydro-2H-benzofuro[2,3-h]chromene-3-carboxylic acid from linear substrates through oxidative couplings. Privileged chromane and tetralin scaffolds were constructed from readily available linear starting materials in the absence of any organohalides and organometallic partners. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Name: 4-Benzyloxyphenol).
4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Name: 4-Benzyloxyphenol
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem