Borgogno, Marco et al. published their research in Journal of Medicinal Chemistry in 2021 | CAS: 109-85-3

2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Computed Properties of C3H9NO

Design, Synthesis, In Vitro and In Vivo Characterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in Down Syndrome was written by Borgogno, Marco;Savardi, Annalisa;Manigrasso, Jacopo;Turci, Alessandra;Portioli, Corinne;Ottonello, Giuliana;Bertozzi, Sine Mandrup;Armirotti, Andrea;Contestabile, Andrea;Cancedda, Laura;De Vivo, Marco. And the article was included in Journal of Medicinal Chemistry in 2021.Computed Properties of C3H9NO The following contents are mentioned in the article:

Intracellular chloride concentration [Cl–]i is defective in several neurol. disorders. In neurons, [Cl–]i is mainly regulated by the action of the Na+-K+-Cl– importer NKCC1 and the K+-Cl– exporter KCC2. Recently, we have reported the discovery of ARN23746(I) as the lead candidate of a novel class of selective inhibitors of NKCC1. Importantly, ARN23746 is able to rescue core symptoms of Down syndrome (DS) and autism in mouse models. Here, we describe the discovery and extensive characterization of this chem. class of selective NKCC1 inhibitors, with focus on ARN23746 and other promising derivatives In particular, we present compound 40 (ARN24092)(II) as a backup/follow-up lead with in vivo efficacy in a mouse model of DS. These results further strengthen the potential of this new class of compounds for the treatment of core symptoms of brain disorders characterized by the defective NKCC1/KCC2 expression ratio. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3Computed Properties of C3H9NO).

2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Computed Properties of C3H9NO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem