Chemoselective dual functionalization of phenols via relay catalysis of borane with different forms was written by Tang, Xiaowen;Luo, Xiang;Su, Qiong;Wei, Gaofei;Meng, Shan-Shui;Chan, Albert S. C.. And the article was included in CCS Chemistry in 2021.Reference of 103-16-2 The following contents are mentioned in the article:
A highly efficient and chemoselective dual functionalization of unprotected phenols with α- or β- hydroxyl acids was presented. A variety of valuable benzofuranones and dihydrocoumarins were delivered in moderate to high yields. D. functional theory (DFT) calculations and control experiments indicated that an untypical Friedel-Crafts alkylation and the subsequent lactonization were catalyzed by the Lewis acid form and the Bronsted acid form of borane, resp. Gram-scale experiments and late-stage functionalization of complex mols. were performed to highlight the utility of this reaction. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Reference of 103-16-2).
4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Reference of 103-16-2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem