α-Lithiobenzyloxy as a Directed Metalation Group in ortho-Lithiation Reactions was written by Sedano, Carlos;Velasco, Rocio;Feberero, Claudia;Suarez-Pantiga, Samuel;Sanz, Roberto. And the article was included in Organic Letters in 2020.COA of Formula: C13H12O2 The following contents are mentioned in the article:
The α-lithiobenzyloxy group, easily generated from aryl benzyl ethers by selective α-lithiation with t-BuLi at low temperature, behaves as a directed metalation group (DMG) providing a direct access to o-lithiophenyl α-lithiobenzyl ethers. This ortho-directing effect is reinforced in substrates bearing an addnl. methoxy group at the meta position. The generated dianions can be reacted with a selection of electrophiles including carboxylic esters and dihalosilanes or germanes, which afford interesting benzofuran, sila(germa)dihydrobenzofuran, and silachromane derivatives from simple aryl benzyl ethers. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2COA of Formula: C13H12O2).
4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.COA of Formula: C13H12O2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem