One-pot access to 2-amino-3-arylbenzofurans: direct entry to polyheterocyclic chemical space was written by Prasad, Sure Siva;Joshi, Dirgha Raj;Lee, Jeong Hwa;Kim, Ikyon. And the article was included in Organic & Biomolecular Chemistry in 2020.Recommanded Product: 103-16-2 The following contents are mentioned in the article:
Two efficient one-pot sequential coupling routes to 2-amino-3-arylbenzofurans and 2-amino-3-arylnaphtho[2,1-b]furans I (R = Cl, propan-2-yl, Ph, etc.; R1 = H, OMe, Ph; RR1 = -OCH2O-; R2 = H, Me; R3 = H, OMe; RR3 = -CH=CH-CH=CH-; Ar = 4-hydroxy-3-methoxyphenyl, thiophen-2-yl, 6-bromo-2H-1,3-benzodioxol-5-yl, etc.) were established. Further ring formation (six- and seven-membered rings) with the resulting amine moiety at the C2 position of benzofurans I were realized, leading to further expansion of benzofuran-based chem. space. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Recommanded Product: 103-16-2).
4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: 103-16-2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem