B(C6F5)3-Catalyzed Hydroarylation of Aryl Alkynes for the Synthesis of 1,1-Diaryl and Triaryl Substituted Alkenes was written by Chen, Hui;Gao, Liuzhou;Liu, Xueting;Wang, Guoqiang;Li, Shuhua. And the article was included in European Journal of Organic Chemistry in 2021.Application In Synthesis of 4-Benzyloxyphenol The following contents are mentioned in the article:
A new strategy for the synthesis of 1,1-diaryl and triaryl-substituted alkenes was developed utilizing B(C6F5)3-catalyzed hydroarylation of alkynes with phenols. The method provided a direct route to ortho-alkenylated phenols with both terminal and internal alkynes. The reactions showed excellent regioselectivity and good stereoselectivity were observed for the hydroarylation of internal alkynes. Computational and exptl. studies suggested that for the reaction of internal alkynes and phenols, an acid-catalyzed isomerization mechanism involving two tertiary carbonium ion intermediates was responsible for the formation of Z-triaryl substituted alkenes. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Application In Synthesis of 4-Benzyloxyphenol).
4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application In Synthesis of 4-Benzyloxyphenol
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem