Impact of light-activated curcumin and curcuminoids films for catheters decontamination was written by Zangirolami, Amanda Cristina;Carbinatto, Fernanda;Filho, Jose Dirceu Vollet;Bagnato, Vanderlei Salvador;Blanco, Kate Cristina. And the article was included in Colloids and Surfaces, B: Biointerfaces in 2022.Electric Literature of C19H16O4 The following contents are mentioned in the article:
Biofilms are microbial communities protected by an extra polymeric matrix, which promotes a defense against antimicrobial agents. Cells attached in surfaces and promote infections. Photodynamic inactivation (PDI) is one of the strategies to eliminate infections due to the facility of use and the absence of resistance by bacteria. The study combines formulation with curcuminoids and with Photogem(R), illuminating them with 450 nm and 630 nm, resp. Films were prepared with pectin, glycerin, Sodium Lauryl Sulfate, curcumin, curcuminoids, or Photogem(R) (0.75; 0.75 mg/mL and 0.03 mg/mL resp.). Bacterial biofilms were formed during 3, 4, or 7 days on catheters and illumination with LED devices at 450 nm and 630 nm.The best PDI applied in S. aureus 7-days biofilm with curcuminoid film. Photogem film was the best strategy for PDI in E. coli 7-day biofilm. Curcumin film promoted similar results with S. aureus and E. coli. Light penetration demonstrated a similar decreased exponential curve along the increase of thickness of biofilm. Curcuminoids, curcumin and Photogem show efficient solubilization and availability in formulation with relevant results in PDI. S aureus biofilms were more susceptible to curcuminoid film. E coli biofilms were more susceptible to Photogem film. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Electric Literature of C19H16O4).
Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Electric Literature of C19H16O4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem