Promising iron(II) complexes of curcumins: designing, density functional theory, and molecular docking was written by Kumar, Ajay;Kumar, Vinod;Kumari, Kamlesh;Jain, Pallavi;Kaushik, Nagendra Kumar;Singh, Prashant. And the article was included in Journal of Physical Organic Chemistry in 2021.Related Products of 33171-05-0 The following contents are mentioned in the article:
Curcumin is the key compound of turmeric and was identified as diferuloylmethane. It can be administered through various routes like orally and inhalation. It is hydrophobic, and the bioavailability for oral administration of curcumin is low. It is an important biol. promising compound and used for the treatment of patients’ suffering from atherosclerosis, colon cancer, hypercholesteremia, inflammatory bowel disease, pancreatic cancer, and so forth. The work aims to design the iron(II) complexes of curcumin and its derivatives The designed complexes were studied by the d. functional theory (DFT) approach for their stability and were investigated based on IR spectra using Gaussian 9.0. Further, curcumin and the iron (II) complexes were explored for their biol. potency as inhibitors against the main protease of SARS-CoV-2, as well as for antimicrobial and antioxidant activities using mol. docking with the iGemDock. Based on the results, it has been observed that among the iron(II) complexes of curcumin, C1 showed promising biol. activities against tyrosinase kinase and the main protease of SARS-CoV-2 as well as satisfactory action against Escherichia coli. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Related Products of 33171-05-0).
Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Related Products of 33171-05-0
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem