Resveratrol and Curcumin for Chagas Disease Treatment-A Systematic Review was written by Imperador, Carlos Henrique Lima;Scarim, Caue Benito;Bosquesi, Priscila Longhin;Lopes, Juliana Romano;Cardinalli Neto, Augusto;Giarolla, Jeanine;Ferreira, Elizabeth Igne;dos Santos, Jean Leandro;Chin, Chung Man. And the article was included in Pharmaceuticals in 2022.Related Products of 33171-05-0 The following contents are mentioned in the article:
Chagas disease (CD) is a neglected protozoan infection caused by Trypanosoma cruzi, which affects about 7 million people worldwide. There are two available drugs in therapeutics, however, they lack effectiveness for the chronic stage-characterized mainly by cardiac (i.e., cardiomyopathy) and digestive manifestations (i.e., megaesophagus, megacolon). Due to the involvement of the immuno-inflammatory pathways in the disease′s progress, compounds exhibiting antioxidant and anti-inflammatory activity seem to be effective for controlling some clin. manifestations, mainly in the chronic phase. Resveratrol (RVT) and curcumin (CUR) are natural compounds with potent antioxidant and anti-inflammatory properties and their cardioprotective effect have been proposed to have benefits to treat CD. Such effects could decrease or block the progression of the disease′s severity. The purpose of this systematic review is to analyze the effectiveness of RVT and CUR in animal and clin. research for the treatment of CD. The study was performed according to PRISMA guidelines and it was registered on PROSPERO (CDR42021293495). The results did not find any clin. study, and the animal research was analyzed according to the SYRCLES risk of bias tools and ARRIVE 2.0 guidelines. We found 9 eligible reports in this study. We also discuss the potential RVT and CUR derivatives for the treatment of CD as well. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Related Products of 33171-05-0).
Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Related Products of 33171-05-0
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem