Solid State Inclusion of the Nonionic Surfactant C12E4 in β-Cyclodextrin, at Various Humidities: A Combined Raman and 13C CP MAS NMR Study was written by Cunha-Silva, Luis;Teixeira-Dias, Jose J. C.. And the article was included in Journal of Physical Chemistry B in 2002.Synthetic Route of C10H22O3 The following contents are mentioned in the article:
The inclusion of the nonionic surfactant α-n-dodecyl-ω-hydroxytetra(oxyethylene), C12E4, in β-cyclodextrin (β-CD), was prepared in the solid state and its structure characterized by powder x-ray diffraction, thermogravimetry, and Raman and 13C CP/MAS NMR spectroscopies. Stepwise dehydration was observed in the thermogram, indicating the presence of energetically distinct water mols. Comparison of the dispersions of 13C chem. shift values for C1 and C4 atoms of the β-CD macrocycle, within a series of inclusion compounds of CnEm homologues, reveals a rather complete symmetrization of the β-CD macrocycle, and the dispersions of 13C shifts for C6 atoms point to the particular sensitivity of these atoms to hydrogen-bonding type of interactions. The integrated intensity of the O-H Raman stretching band for the β-CD inclusion compound of C12E4 is approx. constant for humidities between 20% and 80%. In passing from 15% to 20% of humidity, one observes abrupt relative intensity variations of some Raman bands, in particular at 926 cm-1, and the sudden decrease of the dispersions of 13C chem. shift values for all carbon atoms of the β-CD macrocycle. Overall, the above findings converge to stress the structural relevance of hydration water in the β-CD inclusion compound of C12E4. This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4Synthetic Route of C10H22O3).
2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C10H22O3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem