Hydrotropic Extraction of Carnosic Acid from Rosemary with Short-Chain Alkyl Polyethylene Glycol Ethers was written by Mazaud, Agathe;Lebeuf, Raphael;Laguerre, Mickael;Nardello-Rataj, Veronique. And the article was included in ACS Sustainable Chemistry & Engineering in 2020.Application of 112-59-4 The following contents are mentioned in the article:
Carnosic acid (CA) is a hydrophobic secondary metabolite and the main antioxidant of rosemary. Extractions of CA from whole leaves of rosemary have been performed with aqueous solutions of 12 short-chain alkyl polyethylene glycol ethers, abbreviated as CiEj with i = 4-8 and j = 1-4. Such compounds act as hydrotropes which are known to enhance the solubilization of hydrophobic mols. in water while avoiding the formation of liquid crystals like surfactants. The extractions are compared with those carried out with alcs., sodium xylene sulfonate (SXS) which is an archetypical ionic hydrotrope, and longer CiEj (i = 10 or 12 and j = 4) which behave as true surfactants. C5E2 and C4E1 are the best candidates and provide 1.21 g/L CA in 21 h and 1.02 g/L in 8 h, resp. They are more efficient than SXS and alc. aqueous solutions Correlations between the chem. structure and activity have highlighted three requirements for better performances: (i) a small mol. volume Vm (<250 Å3), (ii) a log P above 1, and (iii) a linear alkyl chain rather than a branched one. Finally, kinetic study and optical microscopy observations of the leaves after extraction give insight into the mode of action of the C4Ej compared to ethanol. Here, we investigate the use of aqueous solutions of nonionic hydrotropes to extract phytochems. in a process that mitigates emissions of volatile organic compounds compared to extraction routes using conventional solvents. This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4Application of 112-59-4).
2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application of 112-59-4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem