Photodynamic therapy of human biliary cancer cell line using combination of phosphorus porphyrins and light emitting diode was written by Matsumoto, Jin;Suzuki, Kou;Yasuda, Masahide;Yamaguchi, Yuya;Hishikawa, Yoshitaka;Imamura, Naoya;Nanashima, Atsushi. And the article was included in Bioorganic & Medicinal Chemistry in 2017.Related Products of 112-59-4 The following contents are mentioned in the article:
A series of phosphorus porphyrin complexes ([(RO)2P(tpp)]Cl, tpp = tetraphenylporphyrinato group, R = -(CH2CH2O)m(CH2)nH; 1a: m = 2, n = 2; 1b: m = 2, n = 4; 1c: m = 2, n = 6; 1d: m = 3, n = 6) were used for the photodynamic therapy (PDT) of human biliary cancer cell line (NOZ) when exposed to the irradiation of light emitting diodes (LEDs). A Dulbecco’s modified Eagle’s medium (DMEM) containing NOZ cells (2000 cell well-1) and 1 (0-100 nM) was introduced into a 96-well microplate and incubated for 24 h to accumulate 1 into the NOZ cells and to multiply the NOZ cells until the cell number reached 104 cells well-1. After replacing the DMEM medium containing 1 with a fresh DMEM medium without 1, the plates were irradiated for 30 min at 610 nm. After incubation was performed for 24 h in dark conditions, the cell viability of the NOZ cells was determined using the MTT assay. The half maximum inhibitory concentrations 50 (IC50) of 1a-1d were found to be in the range of 33.7-58.7 nM for NOZ. These IC50 values for the NOZ were one hundredth the IC50 value (7.57 μM) for mono-
2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Related Products of 112-59-4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem