Preliminary phytochemical and GC-MS analyses of methanolic extract of Blechnum orientale L. collected from Kothiyar, Kanyakumari District, Tamil Nadu, India was written by Fredrick, Raja E.;John, Peter Paul J.. And the article was included in Journal of Drug Delivery and Therapeutics in 2019.Safety of 2-(2-(Hexyloxy)ethoxy)ethanol The following contents are mentioned in the article:
The aim of the study was to screen the phytochems. of methanolic extract of Blechnum orientale L. collected from Kothiyar, located in Kanyakumari district, Tamil Nadu, India. The preliminary phytochem. anal. was carried out by Harborne method, followed by GC-MS anal. In the preliminary phytochem. anal. of Blechnum orientale L., the presence of twelve different types of secondary metabolites such as alkaloids, anthocyanin, anthraquinones, cardiac glycosides, coumarin, diterpenes, emodins, flavonoids, saponins, steroids, tannins and triterpenoids were reported in methanolic extract GC-MS spectrum of methanolic extract of Blechnum orientale L. showed 20 different major peaks which indicated the presence of 20 compounds The prevailing compounds in methanol extract were toluene (1.927min), thiazole, 4,5-dihydro-2-methyl- (2.249min), ethylbenzene (2.466min), benzene, 1,3-dimethyl- (2.523min), phosphine, acetyldimethyl- (2.684min), guanethidine (4.584min), 2-propanamine, n-methyl-n-nitroso- (5.303min), 4h-pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl- (5.435min), diethylene glycol hexyl ether (6.333min), 2,2-dimethylpropanoic acid, nonyl ester (6.655min), 8-thiabicyclo[3.2.1]oct-2-ene (7.156min), 4h-pyrazole, 3-tert-butylsulfanyl-4,4-bistrifluoromethyl- (9.217min), 1,3-benzenediol, 4-propyl- (11.250min), cyclohexanone, 2-methyl-5-(1-methylethenyl)- (13.775min), 2,4-hexadienal, (E,E)- (14.210min), n-hexadecanoic acid (14.966min), phytol (16.451min), 2(1h)-naphthalenone, octahydro-4a-methyl-7-(1-methylethyl)-, (4a.alpha.,7.beta.,8a.beta.)- (16.602min), 7-pentadecyne (16.659min) and 1,4-bis (trimethylsilyl) benzene (20.186min) resp. This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4Safety of 2-(2-(Hexyloxy)ethoxy)ethanol).
2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Safety of 2-(2-(Hexyloxy)ethoxy)ethanol
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem