On December 31, 2022, Huang, Long; Ji, Tengfei; Zhu, Chen; Yue, Huifeng; Zhumabay, Nursaya; Rueping, Magnus published an article.Computed Properties of 93-04-9 The title of the article was Bioinspired desaturation of alcohols enabled by photoredox proton-coupled electron transfer and cobalt dual catalysis. And the article contained the following:
In the biosynthesis of sterols an enzyme-catalyzed demethylation is achieved via a stepwise oxidative transformation of alcs. e.g., 1-(4-methoxyphenyl)cyclodecan-1-ol to olefins e.g., 4-(OCH3)C6H4C(O)(CH2)7CH=CH2. The overall demethylation proceeds through two sequential monooxygenation reactions and a subsequent dehydroformylative saturation To mimic the desaturation processes observed in nature, photoredox proton-coupled electron transfer (PCET) and cobaloxime chem. were successfully integrated for the acceptorless dehydrogenation of alcs. The state-of-the-art remote and precise desaturation of ketones RC(O)(CH2)3CH=CH2 [R = 4-(tert-butoxy)phenyl, phenanthren-9-yl, 1-benzothiophen-2-yl, etc.] proceeds efficiently through the activation of cyclic alcs. I using bond-dissociation free energy (BDFE) as thermodn. driving force. The resulting transient alkoxyl radical allows C-C bond scission to generate the carbon-centered radical remote to the carbonyl moiety. The key intermediate is subsequently combined with cobaloxime photochem. to furnish the alkene. Moreover, the mild protocol can be extended to desaturation of linear alcs. as well as aromatic hydrocarbons. Application to bioactive mols. and natural product derivatives is also presented. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Computed Properties of 93-04-9
The Article related to olefin preparation, alc cross coupling reaction photoredox cobalt catalyst, General Organic Chemistry: Synthetic Methods and other aspects.Computed Properties of 93-04-9
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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem