On January 3, 2006, Bremmell, Kristen E.; Kingshott, Peter; Ademovic, Zahida; Winther-Jensen, Bjorn; Griesser, Hans J. published an article.Reference of 2-(2-(Vinyloxy)ethoxy)ethanol The title of the article was Colloid Probe AFM Investigation of Interactions between Fibrinogen and PEG-Like Plasma Polymer Surfaces. And the article contained the following:
Interaction forces between surfaces designed to be protein resistant and fibrinogen (Fg) were investigated in phosphate-buffered saline with colloid probe at. force microscopy. The surfaces of the silica probes were coated with a layer of fibrinogen mols. by adsorption from the buffer. The technique of low-power, pulsed AC plasma polymerization was used to make poly(ethylene glycol) (PEG)-like coatings on poly(ethylene terephthalate) by using diethylene glycol vinyl ether as the monomer gas. The degree of PEG-like nature of the films was controlled by use of a different effective plasma power in the chamber for each coating, ranging from 0.6 to 3.6 W. This produced a series of thin films with a different number of ether carbons, as assessed by XPS. The interaction force measurements are discussed in relation to trends observed in the reduction of fibrinogen adsorption, as determined quant. by 125I radio-labeling. The plasma polymer coatings with the greatest protein-repelling properties were the most PEG-like in nature and showed the strongest repulsion in interaction force measurements with the fibrinogen-coated probe. Once forced into contact, all the surfaces showed increased adhesion with the protein layer on the probe, and the strength and extension length of adhesion was dependent on both the applied load and the plasma polymer surface chem. When the medium was changed from buffer to water, the adhesion after contact was eliminated and only appeared at much higher loads. This indicates that the structure of the fibrinogen mols. on the probe is changed from an extended conformation in buffer to a flat conformation in water, with the former state allowing for stronger interaction with the polymer chains on the surface. These experiments underline the utility of aqueous surface force measurements toward understanding protein-surface interactions, and developing nonfouling surfaces that confer a steric barrier against protein adsorption. The experimental process involved the reaction of 2-(2-(Vinyloxy)ethoxy)ethanol(cas: 929-37-3).Reference of 2-(2-(Vinyloxy)ethoxy)ethanol
The Article related to colloid probe fibrinogen polyethylene glycol plasma polymer surface, Pharmaceuticals: Prosthetics and Medical Goods and other aspects.Reference of 2-(2-(Vinyloxy)ethoxy)ethanol
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