On January 11, 2018, Su, Ji; Chen, Qian; Lu, Le; Ma, Yuan; Auyoung, George Hong Lok; Hua, Ruimao published an article.SDS of cas: 321-28-8 The title of the article was Base-promoted nucleophilic fluoroarenes substitution of C-F bonds. And the article contained the following:
With the use of KOH/DMSO as the superbase medium, the nucleophilic fluoroarene substitution for C-F bonds was presented. The transformation proceeds smoothly with the use of fluoroarenes such as 2-fluoro-benzamide, 3-fluorobenzaldehyde, 3,4-difluoronitrobenzene, etc. bearing not only electron-withdrawing group, but also electron-donating group and a variety of nucleophiles such as methanol, phenol, dimethylamine, 1H-pyrrole, benzamide, etc.. The double nucleophilic substitution using 3,4-difluoronitrobenzene and nucleophiles bearing ortho-dinucleophilic groups such as 1,2-ethanediol, 1,2-benzenediol, 2-amino-phenol results in the formation of 6-Nitro-2,3-dihydrobenzo[b][1,4]dioxine, 2-Nitrodibenzo[b,e][1,4]dioxine and 2-Nitro-10H-phenoxazine in moderate to good yields. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).SDS of cas: 321-28-8
The Article related to ether preparation, fluoroarene alc nucleophilic substitution, arylamine preparation, amine fluoroarene nucleophilic substitution, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ethers, Sulfides, and The Corresponding Onium Compounds and other aspects.SDS of cas: 321-28-8
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem