Li, Heng; Zhu, Yan; Jiang, Cong; Wei, Jia; Liu, Ping; Sun, Peipei published an article in 2022, the title of the article was HOAc catalyzed three-component reaction for the synthesis of 3,3′-(arylmethylene)bis(1H-indoles).SDS of cas: 157869-15-3 And the article contains the following content:
An efficient HOAc catalyzed three-component cyclization and cascade condensation of o-alkynyl anilines with aromatic aldehydes of 2-(arylethynyl)anilines with arylaldehydes was achieved, which leads to the generation of 3,3′-(arylmethylene)bis(1H-indoles) I [R1 = Ph, 4-MeC6H4, 4-FC6H4, etc.; R2 = 5-Me, 5-Cl, 6-Me, etc.; R3 = Ph, 4-MeC6H4, 4-BrC6H4, etc.] with good to excellent yields and high regioselectivity under transition-metal-free conditions. Four new C-C and C-N bonds were effectively formed in a one-pot procedure. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).SDS of cas: 157869-15-3
The Article related to arylmethylene bis indole green regioselective preparation, ortho alkynyl aniline benzaldehyde three component cyclization cascade condensation, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.SDS of cas: 157869-15-3
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