Pan, Wenjing; Li, Chenchen; Zhu, Haoyin; Li, Fangfang; Li, Tao; Zhao, Wanxiang published an article in 2021, the title of the article was A mild and practical method for deprotection of aryl methyl/benzyl/allyl ethers with HPPh2 and tBuOK.Safety of 2-Methoxynaphthalene And the article contains the following content:
A general method for the demethylation, debenzylation, and deallylation of aryl ethers ROMe (R = C6H5, 3-FC6H4, 2-naphthyl, etc.), R1OCH2Ph (R1 = C6H5, 5,6,7,8-tetrahydronaphthalen-2-yl, 2-naphthyl, etc.) and R2OCH2CH=CH2 (R2 = C6H5, 2,3-dimethylphenyl, 1-naphthyl, etc.) using HPPh2 and tBuOK is reported. The reaction features mild and metal-free reaction conditions, broad substrate scope, good functional group compatibility, and high chem. selectivity towards aryl ethers over aliphatic structures. Notably, this approach is competent to selectively deprotect the allyl or benzyl group, making it a general and practical method in organic synthesis. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Safety of 2-Methoxynaphthalene
The Article related to phenol preparation, aryl methyl ether demethylation, benzyl ether preparation debenzylation, allyl ether preparation deallylation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Safety of 2-Methoxynaphthalene
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem