Gao, Qian; Zhou, Peng; Liu, Feng; Hao, Wen-Juan; Yao, Changsheng; Jiang, Bo; Tu, Shu-Jiang published an article in 2015, the title of the article was Cobalt(II)/silver relay catalytic isocyanide insertion/cycloaddition cascades: a new access to pyrrolo[2,3-b]indoles.Recommanded Product: 2-((4-Methoxyphenyl)ethynyl)aniline And the article contains the following content:
The combination of Co(acac)2 and AgOTf enables the bimetallic relay catalysis reaction of 2-ethynylanilines and isocyanides, allowing easy and low-cost access to new densely functionalized pyrrolo[2,3-b]indoles. The reaction pathway involves a Co(acac)2-catalyzed double isocyanide insertion followed by a silver-enabled 1,3-dipolar cycloaddition [e.g., 2-(phenylethynyl)aniline + isocyanocyclohexane in 1:2 molar ratio → pyrrolo[2,3-b]indole I (up to 86%, under aerobic conditions)]. The synthetic utility of these bicycloaddn. reactions results in subsequent C-C and C-N bond-forming events to rapidly build up mol. complexity. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Recommanded Product: 2-((4-Methoxyphenyl)ethynyl)aniline
The Article related to cobalt silver relay catalytic isocyanide insertion cycloaddition cascade, ethynylanaline reaction isocyanide pyrroloindole preparation, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Recommanded Product: 2-((4-Methoxyphenyl)ethynyl)aniline
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem