On January 31, 1992, Fadel, Antoine published an article.Application In Synthesis of (S)-2-(2-Methoxyphenyl)propanoic acid The title of the article was Optically active arylpropionic acids from the stereoselective alkylation of chiral imide enolates. And the article contained the following:
The chiral imides (3-arylacetyl-4-isopropyl/benzyl-2-oxazolidinones I (R = Q, R1 = H, R3 = CHMe2, CH2 Ph), II (R = Q, R1 = H, R2 = 4-CHEtMe, 2,3-4-MeO, R3 = CHMe2), and III (R = Q, R1 = H, R3 = CHMe2) were alkylated via their imide enolates with Me iodide; subsequent removal of the chiral auxiliary provided readily, with high stereoselectivity, the (S)-2-arylpropionic acids I, II, and III (R = OH), in good yield. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Application In Synthesis of (S)-2-(2-Methoxyphenyl)propanoic acid
The Article related to arylacetyloxazolidinone preparation stereoselective alkylation, stereoselective methylation arylacetyloxazolidinone, arylpropionic acid optically active, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Carboxylic Acids and Peroxycarboxylic Acids and Their Sulfur-Containing Analogs and Salts and other aspects.Application In Synthesis of (S)-2-(2-Methoxyphenyl)propanoic acid
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