On November 19, 1992, Achard, Daniel; Moutonnier, Claude; Peyronel, Jean Francois; Tabart, Michel; Truchon, Alain published a patent.Electric Literature of 81616-80-0 The title of the patent was Preparation and reactions of thiopyranopyrroles and oxide derivatives. And the patent contained the following:
Title compounds I [R = H, allyl, or CR1R2R3, where R1 and R2 are H, (un)substituted Ph (with halo, alkyl, alkyloxy, NO2), and R3 is defined as for R1 or R2 or alkyl or alkyloxyalkyl, where at least one R1-3 is (un)substituted Ph, and n = 0-2], and isomers, are prepared by N-deprotection of the appropriate perhydrothiopyranopyrrole. Salts, isomers, and mixtures of isomers of these compounds are claimed. The above compounds are reacted with alkanoic acids R4CHR5CO2H [e.g., (2-methoxyphenyl)acetic acid] or with an imide analog to give claimed compounds N-substituted I [R = C(:Z)CHR4R5, n = 0-2, Z = O or NH, R4 = (un)substituted Ph (with halo, amino, alkylamino, etc., R5 = H, halo, OH, alkyl, etc.]. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Electric Literature of 81616-80-0
The Article related to thiopyranopyrrole oxide perhydro preparation reaction, perhydrothiopyranopyrrole oxide preparation reaction, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Electric Literature of 81616-80-0
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem