On January 7, 2021, Richards, Kenza; Petit, Eddy; Legrand, Yves-Marie; Grison, Claude published an article.Application of 578-58-5 The title of the article was Eco-Friendly Methodology for the Formation of Aromatic Carbon-Heteroatom Bonds by Using Green Ionic Liquids. And the article contained the following:
A new sustainable method is reported for the formation of aromatic carbon-heteroatom bonds under solvent-free and mild conditions (no co-oxidant, no strong acid and no toxic reagents) by using a new type of green ionic liquid The bromination of methoxy arenes was chosen as a model reaction. The reaction methodol. is based on only using natural sodium bromine, which is transformed into an electrophilic brominating reagent within an ionic liquid, easily prepared from the melted salt FeCl3 hexahydrate. Bromination reactions with this in-situ-generated reagent gave good yields and excellent regioselectivity under simple and environmentally friendly conditions. To understand the unusual bromine polarity reversal of sodium bromine without any strong oxidant, the mol. structure of the reaction medium was characterized by Raman and direct infusion electrospray ionization mass spectroscopy (ESI-MS). An extensive computational investigation using d. functional theory methods was performed to describe a mechanism that suggests indirect oxidation of Br- through new iron adducts. The versatility of the methodol. was successively applied to nitration and thiocyanation of methoxy arenes using KNO3 and KSCN in melted hexahydrated FeCl3. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Application of 578-58-5
The Article related to haloarene green preparation melted ferric chloride ionic liquid, dft-hf calculation, aromatic electrophilic substitution, ionic liquids, mixed melted salts, sustainable chemistry and other aspects.Application of 578-58-5
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem