Pan, Aaron; Chojnacka, Maja; Crowley, Robert III; Gottemann, Lucas; Haines, Brandon E.; Kou, Kevin G. M. published an article in 2022, the title of the article was Synergistic Bronsted/Lewis acid catalyzed aromatic alkylation with unactivated tertiary alcohols or di-tert-butylperoxide to synthesize quaternary carbon centers.COA of Formula: C8H10O And the article contains the following content:
Dual Bronsted/Lewis acid catalysis involving environmentally benign, readily accessible protic acid and iron promotes site-selective tert-butylation of electron-rich arenes using di-tert-butylperoxide. This transformation inspired the development of a synergistic Bronsted/Lewis acid catalyzed aromatic alkylation that fills a gap in the Friedel-Crafts reaction literature by employing unactivated tertiary alcs. as alkylating agents, leading to new quaternary carbon centers. Corroborated by DFT calculations, the Lewis acid serves a role in enhancing the acidity of the Bronsted acid. The use of non-allylic, non-benzylic, and non-propargylic tertiary alcs. represents an underexplored area in Friedel-Crafts reactivity. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).COA of Formula: C8H10O
The Article related to aromatic hydrocarbon ditert butylperoxide acid catalyst regioselective alkylation green, tertiary alc aromatic hydrocarbon acid catalyst regioselective alkylation green, quaternary alkylarene preparation and other aspects.COA of Formula: C8H10O
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem