Liang, Hao; He, Xiaobo; Zhang, Yaqi; Chen, Bin; Ouyang, Jia-sheng; Li, Yongsu; Pan, Bendu; Subba Reddy, Chitreddy V.; Chan, Wesley Ting Kwok; Qiu, Liqin published an article in 2020, the title of the article was Copper-catalyzed (4+1) and (3+2) cyclizations of iodonium ylides with alkynes.Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline And the article contains the following content:
The copper(II)-catalyzed (4+1) cyclizations and copper(I)-catalyzed (3+2) cycloadditions of iodonium ylides R(O)CC(=IC6H5)C(O)R1 [R = R1 = OMe, OEt, OCH2CF3; RR1 = -N(CH3)C(O)N(CH3)-] and 5-methyl-3-(2-phenylethynyl)pyridin-2-amine and alkynes 2-NHR2-4-R3-C6H3CCR4 (R2 = H, CH3; R3 = H, Cl; R4 = Ph, isoquinolin-4-yl, thiophen-2-yl, etc.) and 2-OH-4-R5-5-R6C6H2CCR4 (R5 = R6 = H, R5R6 = -CH=CH-CH=CH-) were successfully developed by employing efficient and safe iodonium ylides instead of traditional diazo compounds Highly functionalized di-Me (E)-3-benzylideneindoline-2,2-dicarboxylates I and II and Me 5-(2-hydroxyphenyl)-2-methoxy-4-phenylfuran-3-carboxylates III were conveniently prepared in moderate to excellent yields. The possible reaction mechanisms were also discussed. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline
The Article related to dimethyl benzylideneindoline dicarboxylate preparation diastereoselective, methyl hydroxyphenyl methoxyphenylfuran carboxylate preparation, iodonium ylide alkyne cycloaddition copper catalyst and other aspects.Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem