Li, Sifeng; Wang, Zihao; Xiao, Haitao; Bian, Zhaoxiang; Wang, Jun published an article in 2020, the title of the article was Enantioselective synthesis of indole derivatives by Rh/Pd relay catalysis and their anti-inflammatory evaluation.Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline And the article contains the following content:
An efficient Rh/Pd relay catalyzed intermol. and cascade intramol. hydroamination for the synthesis of exclusive trans 1-indolyl dihydronaphthalenols (up to 88% yield, 99% ee) I [R = n-Bu, 3-thienyl, phenyl; R1 = H, 5,8-di-Me, 5,8-di-MeO, etc.] was described under mild conditions. Moreover, the in-silico and in-vitro screening showed that the novel 1-indolyl dihydronaphthalenol products were potent lead compounds for treating inflammation disease. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline
The Article related to oxabenzonorbornadiene phenylethynyl aniline palladium rhodium tandem enantioselective diastereoselective hydroamination, indolyl dihydronaphthalenol preparation antiinflammatory mol docking and other aspects.Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline
Referemce:
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Ether | (C2H5)2O – PubChem