Month: October 2022

Katayama, Shintaro; Nishino, Hiroshi published the artcile< Manganese(III)-Based Oxidative Cyclization of N -Aryl-2-oxocycloalkane-1-carboxamides: Synthesis of Spiroindolinones>, Application In Synthesis of 10541-78-3, the main research area is aryl oxocycloalkane carboxamide oxidative cyclization; spiro cycloalkane indoline dione preparation.

The Mn(III)-based oxidative cyclization of twenty-five N-aryl-2-oxocycloalkane-1-carboxamides was investigated. The reactions progressed efficiently to give the desired spiro[cycloalkane-1,3′-indoline]-2,2′-diones in high to quant. yields. The easy conversion of the carbonyl functional group of one of the indoline products, 1′-methylspiro[cyclohexane-1,3′-indoline]-2,2′-dione, was also demonstrated.

Synthesis published new progress about Amides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Application In Synthesis of 10541-78-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Nouaille, Augustin; Pannecoucke, Xavier; Poisson, Thomas; Couve-Bonnaire, Samuel published the artcile< Access to Trisubstituted Fluoroalkenes by Ruthenium-Catalyzed Cross-Metathesis>, Name: 4-(4-Methoxyphenyl)-1-butanol, the main research area is trisubstituted fluoroalkene preparation stereoselective ruthenium catalyst; terminal alkene fluoroalkene cross metathesis.

Although the olefin metathesis reaction is a well-known and powerful strategy to get alkenes, this reaction remained highly challenging with fluororalkenes, especially the Cross-Metathesis (CM) process. Author’s thought was to find an easy accessible, convenient, reactive and post-functionalizable source of fluoroalkene, found as the Me 2-fluoroacrylate. Authors reported herein the efficient ruthenium-catalyzed CM reaction of various terminal and internal alkenes with Me 2-fluoroacrylate giving access, for the first time, to trisubstituted fluoroalkenes stereoselectively. Unprecedent TON for CM involving fluoroalkene, up to 175, have been obtained and the reaction proved to be tolerant and effective with a large range of olefin partners giving fair to high yields in metathesis products.

Advanced Synthesis & Catalysis published new progress about Catalysis. 52244-70-9 belongs to class ethers-buliding-blocks, and the molecular formula is C11H16O2, Name: 4-(4-Methoxyphenyl)-1-butanol.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Wu, Liangying; Song, Yang; Li, Zhanchong; Guo, Jiabao; Yao, Xiaoquan published the artcile< Copper(II)-Catalyzed Aerobic Oxidative Coupling of Arylamines with Hexafluoroisopropanol: An Alternative Methodology for Constructing Fluorinated Compounds>, Formula: C8H11NO, the main research area is fluoroalkylated arylamine green preparation regioselective; arylamine hexafluoroisopropanol oxidative coupling copper catalyst.

The selective functionalization of arylamine derivatives with hexafluoroisopropanol through copper(II)-catalyzed aerobic oxidative coupling was developed to generate various fluoroalkylated arylamines RC(OH)(CF3)2 [R = 4-MeNHC6H4, 1,2,3,4-tetrahydroquinolin-6-yl, 4-Et2NC6H4, etc.] under mild conditions. This method had a wide substrate scope with excellent functional group tolerance and provided the fluorinated products in good to excellent yields. Furthermore, preliminary studies indicated that this reaction occurred via a radical mechanism. This protocol, which uses atm. O2 as an oxidant, provided an alternative green route for constructing fluorinated compounds

Advanced Synthesis & Catalysis published new progress about Aromatic amines Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Formula: C8H11NO.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zheng, Yunlong; Zhang, Sainan; Guo, Jinbiao; Shi, Ruixuan; Yu, Jiangyue; Li, Kaipeng; Li, Ning; Zhang, Zhenjie; Chen, Yao published the artcile< Green and Scalable Fabrication of High-Performance Biocatalysts Using Covalent Organic Frameworks as Enzyme Carriers>, Product Details of C3H7BrO, the main research area is biocatalyst covalent organic framework stability; Biocatalysts; Chiral Catalysis; Covalent Organic Frameworks; Enzyme Immobilization; Porous Materials.

Enzyme immobilization is essential to the com. viability of various critical large-scale biocatalytic processes. However, challenges remain for the immobilization systems, such as difficulties in loading large enzymes, enzyme leaching, and limitations for large-scale fabrication. Herein, we describe a green and scalable strategy to prepare high-performance biocatalysts through in situ assembly of enzymes with covalent organic frameworks (COFs) under ambient conditions (aqueous solution and room temperature). The obtained biocatalysts have exceptional reusability and stability and serve as efficient biocatalysts for important industrial reactions that cannot be efficiently catalyzed by free enzymes or traditional enzyme immobilization systems. Notably, this versatile enzyme immobilization platform is applicable to various COFs and enzymes. The reactions in an aqueous solution occurred within a short timeframe (ca. 10-30 min) and could be scaled up readily (ca. 2.3 g per reaction).

Angewandte Chemie, International Edition published new progress about Adsorption. 6482-24-2 belongs to class ethers-buliding-blocks, and the molecular formula is C3H7BrO, Product Details of C3H7BrO.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Chen, Fenglin; Chen, Ke; Zhang, Yao; He, Yuli; Wang, Yi-Ming; Zhu, Shaolin published the artcile< Remote Migratory Cross-Electrophile Coupling and Olefin Hydroarylation Reactions Enabled by in Situ Generation of NiH>, Related Products of 52244-70-9, the main research area is nickel catalyzed reductive cross electrophile coupling; migratory electrophile coupling olefin hydroarylation ligand nickel controlled; diarylalkane structurally diverse preparation regioselectivity.

A highly efficient strategy for remote reductive cross-electrophile coupling has been developed through the ligand-controlled nickel migration/arylation. This general protocol allows the use of abundant and bench-stable alkyl bromides and aryl bromides for the synthesis of a wide range of structurally diverse 1,1-diarylalkanes in excellent yields and high regioselectivities under mild conditions. Authors also demonstrated that alkyl bromide could be replaced by the proposed olefin intermediate while using Pr bromide/Mn0 as a potential hydride source.

Journal of the American Chemical Society published new progress about Alkanes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (1,1-diarylalkanes). 52244-70-9 belongs to class ethers-buliding-blocks, and the molecular formula is C11H16O2, Related Products of 52244-70-9.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem