73724-45-5, Fmoc-Ser-OH, also known as Fmoc-Ser-OH, is a useful research compound. Its molecular formula is C18H17NO5 and its molecular weight is 327.3 g/mol. The purity is usually 95%.
Fmoc-L-Ser-OH is a synthetic peptide that belongs to the group of glycopeptides. It is used as a model for such compounds and has been shown to have antimicrobial activity in vitro against gram-positive bacteria, especially Staphylococcus epidermidis. This compound was synthesized from 3-mercaptopropionic acid and chloride in the presence of hydroxyl groups and epidermal growth factor. The synthetic pathway can be divided into three steps: (1) condensation of 3-mercaptopropionic acid with hydrochloric acid to yield 3-mercaptoacrylic acid; (2) esterification of 3-mercaptoacrylic acid with glycine to form Fmoc-L-Ser; and (3) deprotection of Fmoc protecting group., Related Products of 73724-45-5
Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 73724-45-5, formula is C18H17NO5, Name is Fmoc-Ser-OH.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Related Products of 73724-45-5.
Takayama, Kentaro;Hitachi, Keisuke;Okamoto, Hideyuki;Saitoh, Mariko;Odagiri, Miki;Ohfusa, Rina;Shimada, Takahiro;Taguchi, Akihiro;Taniguchi, Atsuhiko;Tsuchida, Kunihiro;Hayashi, Yoshio research published 《 Development of Myostatin Inhibitory D-Peptides to Enhance the Potency, Increasing Skeletal Muscle Mass in Mice》, the research content is summarized as follows. Myostatin is a key neg. regulator of skeletal muscle growth, and myostatin inhibitors are attractive tools for the treatment of muscular atrophy. Previously, we reported a series of 14-29 mer peptide myostatin inhibitors, including a potent derivative MIPE-1686, a 16-mer N-terminal-free L-peptide with three unnatural amino acids and a propensity to form β-sheets. However, the biol. stability in vivo of MIPE-1686 is a concern for its development as a drug. In the present study, to develop a more stable myostatin inhibitory D-peptide (MID), various retro-inverso versions of a 16-mer peptide were synthesized. Among these, an arginine-containing derivative, MID-35 shows a potent and equivalent in vitro myostatin inhibitory activity equivalent to that of MIPE-1686 and considerable stability against biodegradation The in vivo potency of MID-35 to increase tibialis anterior muscle mass in mice is significantly enhanced over that of MIPE-1686 and MID-35 can serve as a new entity for the prolonged inactivation of myostatin in skeletal muscle.
73724-45-5, Fmoc-Ser-OH, also known as Fmoc-Ser-OH, is a useful research compound. Its molecular formula is C18H17NO5 and its molecular weight is 327.3 g/mol. The purity is usually 95%.
Fmoc-L-Ser-OH is a synthetic peptide that belongs to the group of glycopeptides. It is used as a model for such compounds and has been shown to have antimicrobial activity in vitro against gram-positive bacteria, especially Staphylococcus epidermidis. This compound was synthesized from 3-mercaptopropionic acid and chloride in the presence of hydroxyl groups and epidermal growth factor. The synthetic pathway can be divided into three steps: (1) condensation of 3-mercaptopropionic acid with hydrochloric acid to yield 3-mercaptoacrylic acid; (2) esterification of 3-mercaptoacrylic acid with glycine to form Fmoc-L-Ser; and (3) deprotection of Fmoc protecting group., Related Products of 73724-45-5
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem