Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Reference of 111-90-0.
Shakeel, Faiyaz;Alshehri, Sultan;Ghoneim, Mohammed M.;Martinez, Fleming;Pena, Maria.;Jouyban, Abolghasem;Acree, William E. research published 《 Solubility of tadalafil in aqueous mixtures of Transcutol and PEG 400 revisited: correlation, thermodynamics and preferential solvation》, the research content is summarized as follows. Mole fraction solubilities of tadalafil (3) in aqueous mixtures of Transcutol and PEG 400 at temperatures from 298.15 to 333.15 K were analyzed following Hildebrand solubility parameters. Cosolvency models for representing tadalafil solubility at various temperatures were also provided for correlation/prediction purposes. Apparent thermodn. quantities for tadalafil dissolution processes were calculated based on van′t Hoff and Gibbs equations. Non-linear enthalpy-entropy compensation was observed for tadalafil transfer from more polar to less polar solvent systems. Preferential solvation parameters of tadalafil at 298.15 and 313.15 K were determined by means of the inverse Kirkwood-Buff integrals (IKBI). Tadalafil is preferentially solvated by water in water-rich mixtures of Transcutol but preferentially solvated by Transcutol in mixtures of 0.12 < x1 < 1.00. In the former case, this result could be due to hydrophobic hydration around the non-polar moieties of tadalafil. Otherwise, tadalafil is preferentially solvated by PEG 400 in all the aqueous mixtures
Reference of 111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem